Advanced Hormone Testing

This profile is designed to reveal how your major hormone systems interact, helping practitioners identify patterns, not just isolated numbers.

Comprehensive hormone panel that measures 14 hormones, secosteroids, and enzymes to assess the health of your thyroid, adrenal, and gonadal endocrine glands, along with vitamin D2 and vitamin D3.

• Steroid hormones (in saliva): Estradiol (E2), Progesterone (Pg), and Testosterone (T)
• Adrenal Hormones (in saliva): DHEA-S (DS), Diurnal Cortisol (sampled 4x to show your full daily cortisol cycle)
• Thyroid hormones (in blood spot): TSH, fT3, fT4, TT4, Tgbn, and TPOab
• Vitamin D (in blood spot): 25-OH, Total (D2, D3)

Hormones keeping you up? Find out with the 24-hour Sleep Balance Profile.

Reveals if your hormones are blocking your sleep.

The Sleep Balance Profile measures cortisol and melatonin 4 times in 24 hours to map your true sleep-wake rhythm.

"Is it hormones? Now you’ll know."

This profile measures your full daily cortisol cycle (Diurnal Cortisol 4x) plus DHEA-S, a key adrenal hormone.

• Why it matters:
  • Low DHEA-S may contribute to chronic fatigue and weight gain.
  • High DHEA-S can promote androgen features in women and may indicate adrenal tumors or PCOS.

Together, these results provide a comprehensive view of adrenal function and overall stress response.

Tests Estradiol (E2), Progesterone (Pg), and Testosterone (T). SHBG in blood spot. (B-240

Tests only Estradiol (E2), Progesterone (Pg), and Testosterone (T). Good for a simple low-cost re-test of these hormones. In saliva.

ZRT Laboratory now offers a comprehensive LC-MS/MS saliva assay that measures the levels of 23 endogenous steroid hormones, including estrogens, progestogens, androgens, glucocorticoids, and mineralocorticoids.

In addition to endogenous hormones, the new assay quantifies

• Melatonin
• Synthetic estrogen: Ethinyl estradiol (EE, commonly found in birth control)
• Hormone synthesis inhibitors: Anastrozole, Letrozole, Finasteride

 How it helps:
By mapping the full steroid hormone cascade, this profile provides deep insights into hormone balance, enzyme function, and potential effects of both natural and pharmaceutical inhibitors, helping guide personalized clinical decisions.

This profile measures 7 key hormones in saliva using the highly precise LC-MS method, available for both females and males: (S-125)

• Steroid hormones: Estradiol (E2), Estrone (E1), Estriol (E3), Progesterone (Pg), Testosterone (T)
• Adrenal & stress hormones: DHEA-S, Cortisol (C)

Why it matters: LC-MS provides a detailed view of the full steroid hormone cascade, offering deeper insight into clinical issues that may arise from insufficient or excessive hormone therapies.

ZRT Vitamin D Sunshine Profile includes (in blood spot):

25-OH D2, 25-OH D3, Total Vitamin D (Calcifediol, also known as calcidiol, 25-hydroxycholecalciferol, or 25-hydroxyvitamin D3)

Vitamin D deficiency can lead to hypertension, joint pain, muscle weakness, and even heart disease and stroke. This test measures both the biologically active (D3) and supplemented (D2) forms.